NC190 sodium
Product Specifications
CAS Number
120602-99-5
Target
Others|||Topoisomerase
Related Pathways
DNA Damage/DNA Repair|||Others
Bioactivity
NC190 is an inhibitor of topoisomerase II that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells when cultured with NC-190 for 48 h (IC50: 0.019 ?g/ml) . NC-190 potently suppressed DNA synthesis with 90% inhibition observed at 0.1 ?g/ml of NC-190.
Smiles
[Na].COc1cc2nc3c4ccccc4c(O)c(C(=O)NCCN(C)C)c3nc2cc1C(O)=O
Molecular Formula
C23H22N4NaO5
Molecular Weight
457.442
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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