Brivanib (alaninate)
Product Specifications
CAS Number
649735-63-7
Target
FGFR, VEGFR, Autophagy
Related Pathways
Angiogenesis, Autophagy, Tyrosine Kinase/Adaptors
Purity
0.9966
Bioactivity
Brivanib Alaninate (BMS-582664) is the alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.
Smiles
C[C@H](COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C)OC(=O)[C@H](C)N
Molecular Formula
C22H24FN5O4
Molecular Weight
441.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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