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Liarozole HCl

Product Specifications

CAS Number

145858-50-0

Target

Others, Cytochromes P450, Retinoid Receptor

Related Pathways

Others, Metabolism

Bioactivity

Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA) -4-hydroxylase, leading to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. It also inhibits aromatase.

Smiles

Cl.ClC1=CC=CC(=C1)C(C=2C=CC=3N=CNC3C2)N4C=NC=C4

Molecular Formula

C17H14Cl2N4

Molecular Weight

345.23

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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