Liarozole HCl
Product Specifications
CAS Number
145858-50-0
Target
Others|||Cytochromes P450|||Retinoid Receptor
Related Pathways
Others|||Metabolism
Bioactivity
Liarozole HCl is a benzimidazole derivative with antineoplastic activity. As a retinoic acid metabolism blocking agent, liarozole inhibits CYP450-dependent all-trans-retinoic acid (ATRA) -4-hydroxylase, leading to an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. It also inhibits aromatase.
Smiles
Cl.ClC1=CC=CC(=C1)C(C=2C=CC=3N=CNC3C2)N4C=NC=C4
Molecular Formula
C17H14Cl2N4
Molecular Weight
345.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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