MC-GGFG-NH-CH2-O-CH2- (s-cyclopropane) -COOH
MC-GGFG-NH-CH2-O-CH2- (s-cyclopropane) -COOH is an ADC linker that can be combined with the cytotoxic Camptothecin (HY-16560) to form an ADC-related drug-linker conjugate (Drug- Linker Conjugates for ADC) .MC-GGFG-NH-CH2-O-CH2-cyclopropane-COOH is conjugated to Camptothecin, which can further bind to the antibody Trastuzumab (HY-P9907) to form Antibody-Drug Conjugates (ADCs) [1].
Product Specifications
CAS Number
[2626930-84-3]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-ggfg-nh-ch2-o-ch2-s-cyclopropane-cooh.html
Purity
98.48
Solubility
10 mM in DMSO
Smiles
O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@@H](C3CC3)C(O)=O)=O)=O)=O)=O)=O
Molecular Formula
C31H40N6O10
Molecular Weight
656.68
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
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