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AKT Kinase Inhibitor (hydrochloride)

AKT Kinase Inhibitor hydrochloride is an Akt kinase inhibitor with anti-tumor activity[1]. AKT Kinase Inhibitor (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[3026697-00-4]

UNSPSC

12352005

Target

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/akt-kinase-inhibitor-hydrochloride.html

Purity

99.39

Solubility

DMSO : 5.88 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCl; heat to 60°C) |H2O : 20 mg/mL (ultrasonic)

Smiles

OCC#CC1=NC=C(C2=C1N=C(N2CC)C3=NON=C3N)OCCCN.[H]Cl

Molecular Formula

C16H20ClN7O3

Molecular Weight

393.83

References & Citations

[1]Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Citation 01

Cell Death Dis. 2024 Nov 9;15 (11) :809.|Biofactors. 2025 May-Jun;51 (3) :e70023.|Cell Commun Signal. 2022 Mar 19;20 (1) :35.|Cell Rep. 2023 May 23;42 (6) :112547.|Cell Stem Cell. 2023 Apr 6;30 (4) :450-459.e9.|Inflammation. 2021 Jun;44 (3) :890-898.|Int J Biol Sci. 2024 Apr 29;20 (7) :2748-2762.|J Cancer. 2021 May 5;12 (13) :3809-3818.|Life Sci. 2019 Aug 15:231:116554.|Mediators Inflamm. 2020 Jun 24;2020:3621261.|Oxid Med Cell Longev. 2021 Mar 19:2021:5595376.|Pharmacol Res. 2024 May 18:107218.|Phytother Res. 2022 Apr;36 (4) :1724-1735.|Research Square Preprint. 2020 Dec.|Research Square Preprint. 2023 May 26.|Small. 2023 Apr;19 (16) :e2207194.

Available Sizes

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