IMM-01
Product Specifications
CAS Number
218795-74-5
Target
Apoptosis, Ras, GTPase
Related Pathways
GPCR/G Protein, Apoptosis, MAPK
Purity
0.9887
Bioactivity
IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia) -related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1].
Smiles
CC(C)(C)NC(=S)N\N=C\C1=C(O)C=C(O)C=C1
Molecular Formula
C12H17N3O2S
Molecular Weight
267.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6173388-01 0.1 mL
DCK (Deoxycytidine Kinase, MGC117410, MGC138632) (Biotin)
Sign In for Pricing
View Details MBS6173388-02 5x 0.1 mL
DCK (Deoxycytidine Kinase, MGC117410, MGC138632) (Biotin)
Sign In for Pricing
View Details 
MBS6365364-01 0.1 mL
ZIC4, NT (ZIC4, Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4) (MaxLight 405)
Sign In for Pricing
View Details 
MBS6365364-02 5x 0.1 mL
ZIC4, NT (ZIC4, Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4) (MaxLight 405)
Sign In for Pricing
View Details