Tolmetin sodium dihydrate
Product Specifications
CAS Number
64490-92-2
Target
COX
Related Pathways
Immunology/Inflammation, Neuroscience
Purity
0.9957
Bioactivity
Tolmetin sodium dihydrate is a potent non-steroidal anti-inflammatory drug (NSAID) that acts as an orally active cyclooxygenase (COX) inhibitor. Tolmetin sodium dihydrate demonstrates inhibitory concentration (IC50) values of 0.35 μM and 0.82 μM for human COX-1 and COX-2 enzymes, respectively, and is widely used as a reference compound for studying the biochemical and pharmacodynamic properties of NSAID-mediated prostaglandin synthesis inhibition.
Smiles
O=C(CC1=CC=C(N1C)C(C2=CC=C(C)C=C2)=O)[O-].[Na+].O.O
Molecular Formula
C15H18NNaO5
Molecular Weight
315.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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