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ETP-45658

Product Specifications

CAS Number

1198357-79-7

Target

MTOR, DNA-PK, PI3K

Related Pathways

PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair

Purity

0.9914

Bioactivity

ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively) . Also inhibits DNA-PK and mTOR (IC50 values are 70.6 and 152 nM respectively) .

Smiles

Cn1ncc2c(nc(nc12)-c1cccc(O)c1)N1CCOCC1

Molecular Formula

C16H17N5O2

Molecular Weight

311.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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