Emofolin sodium
Product Specifications
CAS Number
52386-42-2
Target
Others, Antifolate
Related Pathways
Cell Cycle/Checkpoint, Others
Bioactivity
Emofolin sodium is the sodium salt of a synthetic antimetabolite analogue of folate with antineoplastic activity, which competes for the folate binding site of the enzyme dihydrofolate reductase, resulting in inhibition of tetrahydrofolate synthesis, depletion of nucleotide pools, and inhibition of DNA, RNA and protein synthesis.
Smiles
CN1C2=C(NC(N)=NC2=O)NCC1CCNC3=CC=C(C=C3)C(N[C@H](C([O-])=O)CCC([O-])=O)=O.[Na+].[Na+]
Molecular Formula
C21H25N7Na2O6
Molecular Weight
517.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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