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KALA

KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].

Product Specifications

CAS Number

[187987-64-0]

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/kala.html

Purity

96.10

Solubility

H2O : ≥ 50 mg/mL

Smiles

OC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](CS)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CC1=CN=CN1)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@@H](N)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C144H248N40O35S

Molecular Weight

3131.82

References & Citations

[1]Naoya Miura, et al. Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation. J Pharm Sci. 2017 Oct;106 (10) :3113-3119.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P2530/KALA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P2530/KALA-SDS-MedChemExpress.pdf

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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