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Butyrolactone I

Product Specifications

CAS Number

87414-49-1

Target

NF-κB, Apoptosis, Bcl-2 Family, PERK, ROS, CDK

Related Pathways

Immunology/Inflammation, Cell Cycle/Checkpoint, NF-κB, Apoptosis

Purity

0.98

Bioactivity

Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines.

Smiles

COC(=O)[C@]1(Cc2ccc(O)c(CC=C(C)C)c2)OC(=O)C(O)=C1c1ccc(O)cc1

Molecular Formula

C24H24O7

Molecular Weight

424.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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