Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Linifanib

Product Specifications

CAS Number

796967-16-3

Target

PDGFR, c-Kit, VEGFR, FLT, Apoptosis, CSF-1R, Autophagy, c-Fms

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Autophagy, Apoptosis

Purity

0.9929

Bioactivity

Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM) . Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3) .

Smiles

Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1

Molecular Formula

C21H18FN5O

Molecular Weight

375.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Vmn1r82 Recombinant Protein (Mouse)
RP184433 100 µg

Vmn1r82 Recombinant Protein (Mouse)

Sign In for Pricing
View Details
RND1 Mouse Monoclonal Antibody [Clone ID: OTI4F12]
CF501769 100 µg

RND1 Mouse Monoclonal Antibody [Clone ID: OTI4F12]

Sign In for Pricing
View Details
CD9 Protein Vector (Mouse) (pPB-C-His)
PV163658 500 ng

CD9 Protein Vector (Mouse) (pPB-C-His)

Sign In for Pricing
View Details
Dip2c (NM_001081426) Mouse Tagged ORF Clone Lentiviral Particle
MR221270L4V 200 µL

Dip2c (NM_001081426) Mouse Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details
H2AFB1 Antibody
A24269-50UG 50 µg

H2AFB1 Antibody

Sign In for Pricing
View Details
GLUT3 Antibody
MBS9504617-01 0.05 mL

GLUT3 Antibody

Sign In for Pricing
View Details