Linifanib
Product Specifications
CAS Number
796967-16-3
Target
PDGFR|||c-Kit|||VEGFR|||FLT|||Apoptosis|||CSF-1R|||Autophagy|||c-Fms
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Autophagy|||Apoptosis
Purity
0.9929
Bioactivity
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFR? (IC50: 66 nM) . Linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as FMS-related tyrosine kinase receptor-3 (FLT3) .
Smiles
Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1
Molecular Formula
C21H18FN5O
Molecular Weight
375.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Goat Polyclonal Goat anti-Equine IgG Fc Secondary Antibody [Texas Red]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP1-73474 2 mg
Goat Polyclonal Goat anti-Equine IgG Fc Secondary Antibody [Texas Red]
Ask
View Details 
A700-041 100 µL (10 Blots)
Rabbit anti-CTCF Recombinant Monoclonal Antibody [BLR041F]
Ask
View Details