AZD8309
Product Specifications
CAS Number
333742-48-6
Target
Glutathione Peroxidase, CXCR
Related Pathways
GPCR/G Protein, Autophagy, Immunology/Inflammation, Metabolism
Purity
0.9967
Bioactivity
AZD8309 is a potent, orally available antagonist of the chemokine receptor CXCR2 that regulates neutrophil transport, significantly reduces MPO in the pancreas and lung, and decreases trypsin and elastase activity in the pancreas.AZD8309 can be used to study a range of inflammatory diseases.
Smiles
N([C@@H](CO)C)C1=C2C(=NC(SCC3=C(F)C(F)=CC=C3)=N1)NC(=O)S2
Molecular Formula
C15H14F2N4O2S2
Molecular Weight
384.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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