Binimetinib
Product Specifications
CAS Number
606143-89-9
Target
MEK, Autophagy
Related Pathways
Autophagy, MAPK
Purity
>99.99%
Bioactivity
Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity for the treatment of metastatic melanoma that cannot be resected or has a BRAF V600E or V600K mutation.
Smiles
Cn1cnc2c(F)c(Nc3ccc(Br)cc3F)c(cc12)C(=O)NOCCO
Molecular Formula
C17H15BrF2N4O3
Molecular Weight
441.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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