Cediranib maleate
Product Specifications
CAS Number
857036-77-2
Target
PDGFR, VEGFR, Autophagy
Related Pathways
Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Cediranib maleate (AZD2171 maleate) is an orally active and highly potent VEGF family receptor tyrosine kinase (VEGFR2) inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit, and up-regulates MHC-I through transcriptional modulation in the study of ovarian cancer.
Smiles
C(=C\C(O)=O)\C(O)=O.O(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=CN1)C=4C(F)=C5C(=CC4)NC(C)=C5
Molecular Formula
C29H31FN4O7
Molecular Weight
566.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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