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Cediranib maleate

Product Specifications

CAS Number

857036-77-2

Target

PDGFR, VEGFR, Autophagy

Related Pathways

Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

Cediranib maleate (AZD2171 maleate) is an orally active and highly potent VEGF family receptor tyrosine kinase (VEGFR2) inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit, and up-regulates MHC-I through transcriptional modulation in the study of ovarian cancer.

Smiles

C(=C\C(O)=O)\C(O)=O.O(C=1C2=C(C=C(OCCCN3CCCC3)C(OC)=C2)N=CN1)C=4C(F)=C5C(=CC4)NC(C)=C5

Molecular Formula

C29H31FN4O7

Molecular Weight

566.58

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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