VUF-10497

Product Specifications

CAS Number

1080623-12-6

Target

Histamine Receptor, Others

Related Pathways

Others, GPCR/G Protein, Immunology/Inflammation, Neuroscience

Bioactivity

VUF-10497 is a histamine H4 receptor inverse agonist (pKi = 7.57) . VUF-10497 was found to possess anti-inflammatory properties in vivo in the rat. VUF-10497 also possesses a considerable affinity for the human histamine H1 receptor.

Smiles

N(CC1=CC=CS1)C=2C3=C(N=C(N2)N4CCN(C)CC4)C=CC(Cl)=C3

Molecular Formula

C18H20ClN5S

Molecular Weight

373.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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