Cilengitide
Product Specifications
CAS Number
188968-51-6
Target
Apoptosis, PD-1/PD-L1, Integrin, Autophagy, STAT
Related Pathways
Stem Cells, Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint, Autophagy, JAK/STAT signaling, Cytoskeletal Signaling
Purity
0.998
Bioactivity
Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.
Smiles
CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
Molecular Formula
C27H40N8O7
Molecular Weight
588.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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