What is the catalog number for PD 151746?

The catalog number for PD 151746 is T2493.

What sizes are available for PD 151746?

PD 151746 is available in the following size(s): 5 mg, 1 mL - 10 mM (in DMSO), 10 mg, 25 mg, 50 mg.

How many pack sizes does PD 151746 come in?

PD 151746 is available in 5 different pack sizes.

Is PD 151746 in stock?

PD 151746 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD 151746?

PD 151746 is manufactured by Molfinity.

What is the estimated delivery time for PD 151746?

Estimated delivery time for PD 151746 is approximately 10 business day(s), depending on your location.

PD 151746

Product Specifications

CAS Number

179461-52-0

Target

Proteasome, Cysteine Protease

Related Pathways

Ubiquitination, Proteases/Proteasome

Purity

0.9863

Bioactivity

PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM) . Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].