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SLC3037

Product Specifications

UNSPSC Description

SLC3037 is a NLRP3 inhibitor which blocks NLRP3 from binding to NEK7 or oligomerization, inhibiting inflammasome caused by MSU and other inflammasome activators. SLC3037 can be used for research of gout, cardiovascular diseases, metabolic syndrome or neurodegenerative diseases[1].

Target Antigen

NEKs; NOD-like Receptor (NLR)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/slc3037.html

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CN(CCNC(C1=CC(C2=CSC3=C2N=C(N=C3)NC4=CC=C(C=C4)N5CCN(CC5)CC)=CC=C1)=O)C

Molecular Weight

529.70

References & Citations

[1]Park K, et al. A novel NLRP3 inhibitor as a therapeutic agent against monosodium urate-induced gout. Front Immunol. 2024 Feb 2;14:1307739.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-163358/SLC3037-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-163358/SLC3037-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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