Baricitinib
Product Specifications
CAS Number
1187594-09-7
Target
Chk, JAK, Tyrosine Kinases
Related Pathways
Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis, Cell Cycle/Checkpoint, Stem Cells
Purity
>99.99%
Bioactivity
Baricitinib (INCB028050) is a JAK1 and JAK2 inhibitor (IC50=5.9/5.7 nM) with selective and oral activity. Baricitinib has potential anti-inflammatory, immunomodulatory and anti-tumor activity.
Smiles
CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-c1[nH]cnc2nccc12
Molecular Formula
C16H17N7O2S
Molecular Weight
371.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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