Baricitinib

Product Specifications

CAS Number

1187594-09-7

Target

Chk|||JAK|||Tyrosine Kinases

Related Pathways

Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||JAK/STAT signaling|||Angiogenesis|||Cell Cycle/Checkpoint|||Stem Cells

Purity

>99.99%

Bioactivity

Baricitinib (INCB028050) is a JAK1 and JAK2 inhibitor (IC50=5.9/5.7 nM) with selective and oral activity. Baricitinib has potential anti-inflammatory, immunomodulatory and anti-tumor activity.

Smiles

CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-c1[nH]cnc2nccc12

Molecular Formula

C16H17N7O2S

Molecular Weight

371.42

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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