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SKA-111

Product Specifications

CAS Number

1369170-24-0

Target

Potassium Channel

Related Pathways

Membrane transporter/Ion channel

Purity

0.999

Bioactivity

SKA-111 is a selective calcium-activated potassium phannel (potassium phannel) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve and the S4-S5 junction and ameliorates Bradykinin-induced dilation of coronary arteries in the isolated rat heart, which can be used for the study of cardiovascular diseases. study of cardiovascular diseases.

Smiles

NC1=NC=2C=3C(C(C)=CC2S1)=CC=CC3

Molecular Formula

C12H10N2S

Molecular Weight

214.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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