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SIRT6-IN-5

Product Specifications

CAS Number

891002-11-2

Target

Sirtuin

Related Pathways

DNA Damage/DNA Repair|||Chromatin/Epigenetic

Purity

0.9923

Bioactivity

SIRT6-IN-5 (SIRT6 inhibitor 5) is a potent and selective SIRT6 inhibitor with an IC50 value of 34 ?M.SIRT6-IN-5 is immunosuppressive and chemo-sensitizing, increases H3K9 acetylation and glucose uptake in cultured cells, and reduces T-cell proliferation.

Smiles

N(C(=O)C1=CC=C(NC(=O)C2=CC=CO2)C=C1)C3=CC(C(O)=O)=C(O)C=C3

Molecular Formula

C19H14N2O6

Molecular Weight

366.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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