SCH-336
Product Specifications
CAS Number
447459-51-0
Target
Cannabinoid Receptor
Related Pathways
GPCR/G Protein
Purity
0.97
Bioactivity
SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100 times more selective to CB2 receptor than CB1. SCH-336 reduced the binding of guanosine 5' -3-o - (sulfur) triphosphate to the membrane containing hCB, inhibited BaF3/CB2 cell migration, inhibited leukocyte migration in mouse delayed hypersensitivity models, and inhibited antigen-induced pulmonary eosinophilia in mouse allergy models.
Smiles
S(=O)(=O)(C1=C(S(=O)(=O)C2=CC=C(OC)C=C2)C=C(OC)C=C1)C3=CC=C([C@@H](NS(C)(=O)=O)C)C=C3
Molecular Formula
C23H25NO8S3
Molecular Weight
539.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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