Rubone
Product Specifications
CAS Number
73694-15-2
Target
MicroRNA
Related Pathways
Chromatin/Epigenetic
Purity
0.9892
Bioactivity
Rubone (2'-Hydroxy-2,4,4',5,6'-pentamethoxychalcone), a natural product and a modulator of miR-34a (microRNA-34), upregulates miR-34a expression in a p53-dependent manner, which in turn downregulates the expression of downstream targets Bcl-2, cyclin-D1, CDK6, SIRT1, and FOXP1, thereby inhibiting tumor growth and reversal of hepatocellular carcinoma (HCC) and chemoresistance in prostate cancer.
Smiles
C(=C/C(=O)C1=C(OC)C=C(OC)C=C1O)\C2=C(OC)C=C(OC)C(OC)=C2
Molecular Formula
C20H22O7
Molecular Weight
374.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K1543508 1.0 µg DNA
OR8B12 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
Sign In for Pricing
View Details 41275121 3x 1.0µg DNA
RPL27AP5 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details 
MBS7201029-01 48 Well
Canine Ankyrin repeat domain-containing protein 18B (ANKRD18B) ELISA Kit
Sign In for Pricing
View Details MBS7201029-02 96 Well
Canine Ankyrin repeat domain-containing protein 18B (ANKRD18B) ELISA Kit
Sign In for Pricing
View Details MBS7201029-03 5x 96 Well
Canine Ankyrin repeat domain-containing protein 18B (ANKRD18B) ELISA Kit
Sign In for Pricing
View Details