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CGI-1746

Product Specifications

CAS Number

910232-84-7

Target

Autophagy, BTK

Related Pathways

Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9827

Bioactivity

CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.

Smiles

CC1=C(C=CC=C1NC(=O)C2=CC=C(C(C)(C)C)C=C2)C=3N=C(NC4=CC=C(C(=O)N5CCOCC5)C=C4)C(=O)N(C)C3

Molecular Formula

C34H37N5O4

Molecular Weight

579.69

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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