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RLX

Product Specifications

CAS Number

4425-23-4

Target

Others, PI3K, Akt, FOXO

Related Pathways

Others, Apoptosis, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

Purity

0.9981

Bioactivity

RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer activity against tumour cell lines such as colon cancer, inducing sub-G1 arrest and mitochondrial potential loss, thereby inhibiting tumour growth. RLX also exhibits antitussive and anti-asthmatic activity, reducing eosinophils and total lymphocytes in bronchoalveolar lavage (BAL) fluid, and exhibits toxicity toward A549 cells.

Smiles

O=C1C=2C=CC=CC2N=C3N1CCCCC3

Molecular Formula

C13H14N2O

Molecular Weight

214.26

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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