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PKR-IN-C51

Product Specifications

CAS Number

1314594-23-4

Target

Serine Protease|||Serine/threonin kinase

Related Pathways

Cell Cycle/Checkpoint|||Proteases/Proteasome|||Metabolism

Purity

0.9894

Bioactivity

PKR-IN-C51 is a dose-dependent and ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation in mouse macrophages with an IC50=9 ?M and Ki=3.4 ?M.Interferon-induced double-stranded RNA-activated protein kinase (PKR) is a widely expressed Ser/Thr kinase.

Smiles

N1=CC=C(N=C1NCCC2=CNC=3C=CC=CC32)C=4C=5C=CC=CC5NC4C

Molecular Formula

C23H21N5

Molecular Weight

367.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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