PKR-IN-C51
Product Specifications
CAS Number
1314594-23-4
Target
Serine Protease|||Serine/threonin kinase
Related Pathways
Cell Cycle/Checkpoint|||Proteases/Proteasome|||Metabolism
Purity
0.9894
Bioactivity
PKR-IN-C51 is a dose-dependent and ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation in mouse macrophages with an IC50=9 ?M and Ki=3.4 ?M.Interferon-induced double-stranded RNA-activated protein kinase (PKR) is a widely expressed Ser/Thr kinase.
Smiles
N1=CC=C(N=C1NCCC2=CNC=3C=CC=CC32)C=4C=5C=CC=CC5NC4C
Molecular Formula
C23H21N5
Molecular Weight
367.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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