PF-06372222
Product Specifications
CAS Number
1407592-99-7
Target
Others|||Glucagon Receptor
Related Pathways
Others|||GPCR/G Protein
Bioactivity
PF-06372222 is a small-molecule negative allosteric modulator of the glucagon receptor (GCGR) . PF-06372222 is also an antagonist for glucagon-like peptide-1 receptor GLP-1R, which inhibits glucagon secretion and glucose-dependent insulin secretion.
Smiles
[C@@H](NC=1C=CC(=NC1)N2C=C(C(F)(F)F)N=C2)(C3CC(C)(C)C3)C4=CC=C(C(NCCC(O)=O)=O)C=C4
Molecular Formula
C26H28F3N5O3
Molecular Weight
515.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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