What is the catalog number for NHI-2?

The catalog number for NHI-2 is T24530.

What sizes are available for NHI-2?

NHI-2 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg.

How many pack sizes does NHI-2 come in?

NHI-2 is available in 7 different pack sizes.

NHI-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NHI-2?

NHI-2 is manufactured by Molfinity.

What is the estimated delivery time for NHI-2?

Estimated delivery time for NHI-2 is approximately 10 business day(s), depending on your location.

NHI-2

Product Specifications

CAS Number

1269802-97-2

Target

Apoptosis, Dehydrogenase

Related Pathways

Apoptosis, Metabolism

Purity

0.99981

Bioactivity

NHI-2 is a lactate dehydrogenase A (LDHA) inhibitor with an IC50 value of 14.7 μM, demonstrating high selectivity for LDHA over LDHB, for which the IC50 is 55.8 μM. NHI-2 functions as an efficient anti-glycolytic agent, enhancing apoptosis, inducing cell cycle arrest at the S and G2 phases, and exerting broad-spectrum antiproliferative effects in cancer cells. NHI-2 additionally affects extracellular acidification rates and ATP production and has demonstrated tumor growth suppression in murine B78 melanoma models, highlighting its role in cancer metabolism research.