ML399
Product Specifications
CAS Number
1560968-49-1
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Purity
0.982
Bioactivity
ML399 is the menin--MLL interaction inhibitor that demonstrates strong and selective effects in MLL leukemia cells, and ML399 validates a specific mechanism of action by blocking oncogenic menin-MLL signaling, providing a valuable chemical probe for functional genomics and leukemia-targeted therapeutic strategy development while enabling comprehensive mechanistic and translational hematologic cancer research.
Smiles
[C@@](O)(C1=CC(F)=CC=C1)(C2CCN(CCCOC3=CC=C(C#N)C=C3)CC2)C4=CC=CC=N4
Molecular Formula
C27H28FN3O2
Molecular Weight
445.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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