Milademetan free base
Product Specifications
CAS Number
1398569-75-9
Target
Others|||MDM-2/p53
Related Pathways
Apoptosis|||Others
Bioactivity
Milademetan (DS-3032b or DS-3032) is a potent and selective MDM2 inhibitor with potential antineoplastic activity. Milademetan (p.o.) binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53.
Smiles
Cc1ccc(cc1)S(O)(=O)=O.CC1(C)CCC2(CC1)N[C@H]([C@H](c1ccnc(Cl)c1F)[C@]21C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@@H]1CC[C@H](OC1)C(N)=O
Molecular Formula
C37H42Cl2FN5O7S
Molecular Weight
790.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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