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MI-1481

Product Specifications

CAS Number

1887178-64-4

Target

Epigenetic Reader Domain, Others

Related Pathways

Others, Chromatin/Epigenetic

Bioactivity

MI-1481 is an effective MML1 inhibitor (IC50: 3.6 nM) . MI-1481 showed very potent inhibition of the menin-MLL1 interaction (IC50: 3.6 nM) . MI-1481 also demonstrates pronounced activity in MLL leukemia cells and in vivo in MLL leukemia models.

Smiles

C(N1C=2C(C=C1C#N)=C(C)C(CN3CCC(NC4=C5C(SC(CC(F)(F)F)=C5)=NC=N4)CC3)=CC2)[C@@H]6CNC(=O)CO6

Molecular Formula

C29H30F3N7O2S

Molecular Weight

597.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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