L-368899 free base
Product Specifications
CAS Number
148927-60-0
Target
Oxytocin Receptor|||Others
Related Pathways
Others|||Endocrinology/Hormones|||GPCR/G Protein
Bioactivity
L-368899 is a non-peptide and orally active antagonist of oxytocin receptor (IC50: 8.9 nM) . It displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50: 370 and 570 nM respectively) .
Smiles
[H][C@@]12CC[C@@](CS(=O)(=O)N3CCN(CC3)c3ccccc3C)([C@H](C1)NC(=O)[C@@H](N)CCS(C)(=O)=O)C2(C)C|@:35,TLB:24:22:35:2.3|
Molecular Formula
C26H42N4O5S2
Molecular Weight
554.77
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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