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L-368899 free base

Product Specifications

CAS Number

148927-60-0

Target

Oxytocin Receptor|||Others

Related Pathways

Others|||Endocrinology/Hormones|||GPCR/G Protein

Bioactivity

L-368899 is a non-peptide and orally active antagonist of oxytocin receptor (IC50: 8.9 nM) . It displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50: 370 and 570 nM respectively) .

Smiles

[H][C@@]12CC[C@@](CS(=O)(=O)N3CCN(CC3)c3ccccc3C)([C@H](C1)NC(=O)[C@@H](N)CCS(C)(=O)=O)C2(C)C|@:35,TLB:24:22:35:2.3|

Molecular Formula

C26H42N4O5S2

Molecular Weight

554.77

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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