EPZ011989

Product Specifications

CAS Number

1598383-40-4

Target

Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic

Purity

0.9981

Bioactivity

EPZ011989 is a effective, specific orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 Y646 and EZH2 wt; 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.

Smiles

CCN([C@H]1CC[C@@H](CC1)N(C)CCOC)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C#CCN1CCOCC1

Molecular Formula

C35H51N5O4

Molecular Weight

605.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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