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XX-650-23

Product Specifications

CAS Number

117739-40-9

Target

Epigenetic Reader Domain, Apoptosis

Related Pathways

Chromatin/Epigenetic, Apoptosis

Purity

0.9701

Bioactivity

XX-650-23 is a small molecule CREB inhibitor that blocks the critical interaction between CREB and its required coactivator, CBP (CREB-binding protein), inducing apoptosis and cell cycle arrest in AML cells, and can be used in the study of acute myelogenous leukaemia (AML) .

Smiles

N#CC1=CC=C(C=C1)NC(=O)C2=CC=3C=CC=CC3C=C2O

Molecular Formula

C18H12N2O2

Molecular Weight

288.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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