IRAK4-IN-16
Product Specifications
CAS Number
1812188-83-2
Target
IRAK, Others
Related Pathways
Immunology/Inflammation, Others, NF-κB
Bioactivity
IRAK4-IN-16 (compound 4) is a potent inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with an IC50 of 2.5 nM. It exhibits cytotoxicity against OCI-LY10, TMD8, Ramos, and HT cells, with IC50 values of 0.2, 0.2, 0.6, and 2.7 μM, respectively [1].
Smiles
C(NC=1C(C(F)F)=NN(C)C1)(=O)C2=C3N(N=C2)C=CC(N[C@@H]4CCCNC4)=N3
Molecular Formula
C17H20F2N8O
Molecular Weight
390.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VACY-1022-CY148 1 Kit
Diphtheria Toxoid IgG Antibody ELISA Kit, Human
Sign In for Pricing
View Details 