IHR-1
Product Specifications
CAS Number
548779-60-8
Target
Smo
Related Pathways
Stem Cells
Purity
0.986
Bioactivity
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM) . Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Smiles
Clc1ccc(Cl)c(c1)C(=O)Nc1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1
Molecular Formula
C20H12Cl4N2O2
Molecular Weight
454.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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