ISD (sodium)
ISD (interferon stimulatory DNA) sodium is a non-CpG oligomer from the Listeria monocytogenes genome. When transfected into cells, ISD sodium strongly enhances the expression of IFN-β. This ISD-induced response is mediated by the STING-TBK1-IRF3 signaling axis[1].
Product Specifications
UNSPSC
12352208
Target
STING
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/isd-sodium.html
Purity
98.02
Solubility
10 mM in DMSO|10 mM in H2O
Smiles
[ISD(sodium)]
References & Citations
[1]Stetson DB, Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity. 2006;24 (1) :93-103.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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