DI-404
Product Specifications
CAS Number
2187412-79-7
Target
E1/E2/E3 Enzyme, Others
Related Pathways
Others, Ubiquitination
Bioactivity
DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM) . DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members.
Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H]1C=2C(OCC1)=CC=CC2)=O)CCCCN)=O)[C@H]3CCOCC3)=O)NC(CC)=O)C=4SC=5C(N4)=CC=C(Cl)C5
Molecular Formula
C35H45ClN6O6S
Molecular Weight
713.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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