Dacomitinib metabolite M2

1262034-38-7

EGFR, Others

JAK/STAT signaling, Others, Angiogenesis, Tyrosine Kinase/Adaptors

Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.

N(C=1C2=C(C=C(OC)C(NC(CC(CN3CCCCC3)SC[C@@H](C(O)=O)N)=O)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4

C27H32ClFN6O4S

591.1

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