Cosalane
Product Specifications
CAS Number
154212-56-3
Target
CXCR, CCR, HIV Protease, HSV
Related Pathways
Microbiology/Virology, Autophagy, Immunology/Inflammation, Proteases/Proteasome, GPCR/G Protein
Purity
>99.99%
Bioactivity
Cosalane (NSC 658586) is an HIV replication inhibitor, an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice, with antiviral activity that blocks the binding of CCR7 to its natural ligands, CCL19 and CCL21.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC[C@]1(C[C@@H](CCC=C(C5=CC(C(O)=O)=C(O)C(Cl)=C5)C6=CC(C(O)=O)=C(O)C(Cl)=C6)CC2)[H])[H])[H]
Molecular Formula
C45H60Cl2O6
Molecular Weight
767.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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