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CLK1/2-IN-3

Product Specifications

CAS Number

1005784-60-0

Target

Serine/threonin kinase, CDK

Related Pathways

Metabolism, Cell Cycle/Checkpoint

Purity

0.9904

Bioactivity

CLK1/2-IN-3 (Cpd-3) is a potent and selective CLK1 and CLK2 inhibitor with antiproliferative activity and inhibits the activities of CLK1, CLK2, SRPK1, SRPK2, and SRPK3.CLK1/2-IN-3 induces nuclear speckle enlargement, which induces S6K pre-mRNA-selective splicing and subsequent inhibition of cell growth of multiple cancer cell types. cancer cell types cell growth.

Smiles

N(C(=O)C1=CC=C(C(CO)(C)C)C=C1)C2=CN3C(=N2)C=CC(=C3)C=4C=NNC4

Molecular Formula

C21H21N5O2

Molecular Weight

375.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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