Vemurafenib
Product Specifications
CAS Number
918504-65-1
Target
Autophagy, Raf, MAPK, Src, ACK1
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, MAPK, Autophagy
Purity
0.9965
Bioactivity
Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently. Vemurafenib exhibits antitumor activity and is used for the treatment of BRAF V600E mutation-positive melanoma.
Smiles
C(=O)(C=1C=2C(NC1)=NC=C(C2)C3=CC=C(Cl)C=C3)C4=C(F)C(NS(CCC)(=O)=O)=CC=C4F
Molecular Formula
C23H18ClF2N3O3S
Molecular Weight
489.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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