Abemaciclib
Product Specifications
CAS Number
1231929-97-7
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9987
Bioactivity
Abemaciclib (LY2835219) is a dual inhibitor of CDK4/6 (IC50=2/10 nM) with selectivity and specificity. Abemaciclib has antitumor activity and is used to treat advanced or metastatic breast cancer.
Smiles
C(C)(C)N1C=2C(=C(F)C=C(C2)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)N=C1C
Molecular Formula
C27H32F2N8
Molecular Weight
506.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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